牙齿热疼痛流体动力学假说的证实与完善

林敏 1; 刘少宝 1; 牛林 1; 3; 徐峰 1; 2; 4; 卢天健 1

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牙齿热疼痛流体动力学假说的证实与完善

更新时间：2025-07-09

- 牙齿热疼痛流体动力学假说的证实与完善
- Modeling and Perfecting of Hydrodynamic Hypothesis for Tooth Thermal Pain
- 西安交通大学学报 2011年45卷第12期页码：117-122
- 作者机构：
  
  1. 西安交通大学生物医学工程与生物力学中心,西安,710049
  2. 西安交通大学生命科学与技术学院,西安,710049
- 作者简介：
- 基金信息：
  
  : 2011-05-10. 作者简介: 林敏(1982-),男,讲师;卢天健(通信作者),男,教授,博士生导师. 基金项目: 国家自然科学基金资助项目(10825210,10872157);国家“111引智计划”资助项目(B06024)
- DOI：
  中图分类号： Q66
- 网络首发：2011-12-10，
  
  纸质出版：2011
- 稿件说明：
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林敏 1, 刘少宝 1, 牛林 1, 等. 牙齿热疼痛流体动力学假说的证实与完善[J]. 西安交通大学学报, 2011,45(12):117-122.

Modeling and Perfecting of Hydrodynamic Hypothesis for Tooth Thermal Pain[J]. 2011, 45(12): 117-122.
林敏 1, 刘少宝 1, 牛林 1, 等. 牙齿热疼痛流体动力学假说的证实与完善[J]. 西安交通大学学报, 2011,45(12):117-122. DOI：

Modeling and Perfecting of Hydrodynamic Hypothesis for Tooth Thermal Pain[J]. 2011, 45(12): 117-122. DOI：

摘要

基于牙齿热疼痛流体动力学假说

建立了牙体组织层状结构的生物热-力耦合模型

模拟了冷热刺激下牙本质小管的变形以及牙本质小管液的流动

从理论上证实了冷热刺激下牙本质小管的热变形是导致小管液快速流动的主要机理

阐释了牙髓神经放电特征

成功解释了牙齿在冷热刺激下分别表现为锐痛与钝痛的现象.首次从理论上证实并完善了1962年Brännström等人针对牙齿冷热疼痛机制提出的流体动力学假说.

Abstract

Based on the hydrodynamic hypothesis for tooth thermal pain

a thermo-mechanical model is proposed to simulate dentinal fluid flow under thermal stimulation. It is found that

upon applying the thermal stimulation

other than thermally-induced fluid expansion/contraction

the deformation of dentine micro tubules is responsible for the rapid response of fluid flow in dentinal tubules. The mechanism underlying the difference in neural discharge patterns caused by cooling and those by heating is provided. It is the first time that the hydrodynamic hypothesis proposed by Brännström in 1962 is theoretically demonstrated and perfected.

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references

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