Preparation and Performance Study of Polyetheretherketone/Hydroxyapatite Composite Implants

doi:10.7652/xjtuxb201904011

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Preparation and Performance Study of Polyetheretherketone/Hydroxyapatite Composite Implants

更新时间：2025-07-09

- Preparation and Performance Study of Polyetheretherketone/Hydroxyapatite Composite Implants
- Vol. 53, Issue 4, Pages: 72-78(2019)
- 作者机构：
  
  西安交通大学机械制造系统工程国家重点实验室,西安,710049
- 作者简介：
- 基金信息：
- DOI：10.7652/xjtuxb201904011
  CLC： TG156
- Online First：10 April 2019，
  
  Published：2019
- 稿件说明：
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Preparation and Performance Study of Polyetheretherketone/Hydroxyapatite Composite Implants[J]. 2019, 53(4): 72-78.
DOI：

Preparation and Performance Study of Polyetheretherketone/Hydroxyapatite Composite Implants[J]. 2019, 53(4): 72-78. DOI： 10.7652/xjtuxb201904011.

摘要

为了解决聚醚醚酮(PEEK)无法满足植入物材料的生物学性能要求的难题

提出采用熔融沉积成形(FDM)和溶液共混的方法

在聚醚醚酮基体表面涂覆聚醚醚酮/羟基磷灰石(HA)复合涂层

增强涂层与基体之间的结合

制备出高强度高生物活性的复合植入物

并研究了HA含量、烧结温度和烧结时间对复合植入物力学性能的影响。根据缺损模型制备出了具有复杂结构的个性化狗下颌髁状突PEEK/HA复合假体

对假体形状精度进行了评价

完成了假体置换实验

结合细胞毒性实验对复合植入物的生物相容性进行了评价。研究结果表明:HA的质量分数为40%时

涂层与基体结合强度较好。当烧结温度为240 ℃、烧结时间为20 min时

涂覆效果和样件的力学性能最好。细胞毒性实验和假体置换实验结果表明

采用该工艺制造的复合假体具有优良的生物相容性

且形状精度满足使用要求。

Abstract

A method for fabricating high-strength and high-biological composite implants is proposed to solve the problem that the polyetheretherketone(PEEK)cannot meet the implant materials requirements for biological properties. The method combines FDM and solution blending

and applies PEEK/HA on the surface of PEEK to enhance the bonding strength between the coating and substrate. The mechanical properties of the composite implants are studied and their biological properties are evaluated by cytotoxicity experiments and implant replacement experiments. A personalized mandibular condylar PEEK/HA composite implant with complex structure is fabricated based on a defect model

and its accuracy is evaluated. Results show that when the mass fraction of HA is 40%

the bonding strength between the coating and the substrate is higher. When the sintering temperature is 240 ℃ and the sintering time is 20 minutes

both the coating effect and the mechanical properties are the best. Results of cytotoxicity experiments and implant replacement experiments show that the composite implant has excellent biocompatibility

and the shape accuracy of the implant meets operating requirements.

关键词

Keywords

references

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