Process of Surface Modification with Multi-Walled Carbon Nanotubes for Deep Brain Stimulation Electrodes

doi:10.7652/xjtuxb201902019

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Process of Surface Modification with Multi-Walled Carbon Nanotubes for Deep Brain Stimulation Electrodes

更新时间：2025-07-09

- Process of Surface Modification with Multi-Walled Carbon Nanotubes for Deep Brain Stimulation Electrodes
- Vol. 53, Issue 2, Pages: 142-149(2019)
- 作者机构：
  
  西安交通大学机械制造系统工程国家重点实验室,西安,710049
- 作者简介：
- 基金信息：
- DOI：10.7652/xjtuxb201902019
  CLC： TG156
- Online First：10 February 2019，
  
  Published：2019
- 稿件说明：
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Process of Surface Modification with Multi-Walled Carbon Nanotubes for Deep Brain Stimulation Electrodes[J]. 2019, 53(2): 142-149.
DOI：

Process of Surface Modification with Multi-Walled Carbon Nanotubes for Deep Brain Stimulation Electrodes[J]. 2019, 53(2): 142-149. DOI： 10.7652/xjtuxb201902019.

摘要

为了提高脑深部刺激(DBS)电极组织界面的电学性能和生物相容性

提出一种直流电泳沉积多壁碳纳米管(MWCNTs)制备电极表面纳米结构对电极进行修饰改性的方法

将不锈钢片和铜电极接在直流电源的阳极和阴极

放入经过纯化处理和功能化处理后配制成的MWCNTs悬浊液中

设置电压和电泳时间

即可在不锈钢片上沉积多壁碳纳米管。对多壁碳纳米管修饰电极的电泳沉积工艺进行了研究

评价了电泳沉积形成的多壁碳纳米管薄膜的稳定性、材料成分和生物学特性。研究结果表明

电泳沉积多壁碳纳米管的最佳参数是20 V和7 min

电泳沉积可以在电极表面形成20～100 nm的碳纳米管结构膜层

膜层表面颗粒均匀

排列致密

连续性好

没有裂纹

且薄膜的纯度较高

生物相容性良好

具有较好的电化学稳定性

但机械稳定性有待提高。该方法在保证电极-组织界面生物相容性的基础上

能有效避免电极电性能下降

从而提高电极的综合性能。

Abstract

To improve the electrical performance and biocompatibility of the deep brain stimulation(DBS)electrode-tissue interface

DC electrophoretic deposition of multi-walled carbon nanotubes to modify electrode is proposed. The stainless steel plate and copper electrode are connected to the anode and cathode of DC power supply

and put into the suspension of MWCNTs prepared after purification and functionalization. The multi-walled carbon nanotubes can be deposited on the stainless steel plate by setting voltage and electrophoresis time. The electrophoretic deposition process

stability and material composition of multi-walled carbon nanotubes film formed by electrophoretic deposition is investigated and the biological characters of modified electrodes are evaluated. The results show that the best combination parameters of the electrophoretic deposition of multi-walled carbon nanotubes are 20 V and 7 min. 20-100 nm carbon nanotube film can be formed on the electrode surface by electrophoretic deposition

the film with good continuity and high purity and without cracks is endowed with good biocompatibility and electrochemical stability

but it is suggested to strengthen the mechanical stability. This strategy ensures the biocompatibility of electrode-tissue interface and effectively avoids degradation of electrode electrical properties.

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references

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