Study on Surface Sterilization of Remote Argon Plasma

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Study on Surface Sterilization of Remote Argon Plasma

更新时间：2025-07-09

- Study on Surface Sterilization of Remote Argon Plasma
- Vol. 44, Issue 9, Pages: 109-114(2010)
- 作者机构：
  
  1. 西安交通大学环境科学与工程系,西安,710049
  2. 西安交通大学动力工程多相流国家重点实验室,西安,710049
- 作者简介：
- 基金信息：
- DOI：
  CLC： R18
- Online First：10 September 2010，
  
  Published：2010
- 稿件说明：
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Study on Surface Sterilization of Remote Argon Plasma[J]. 2010, 44(9): 109-114.
DOI：

Study on Surface Sterilization of Remote Argon Plasma[J]. 2010, 44(9): 109-114. DOI：

摘要

研究了射频放电远程氩等离子体对材料表面金黄色葡萄球菌的灭活效果及动力学

并结合等离子体场中活性粒子的分布状态

分析了灭菌机理.结果表明:远程氩等离子体的灭菌效果强烈依赖于等离子体处理条件

且随处理时间的延长

不同放电距离处的灭菌速率均分为3段逐渐减慢

并在放电功率100 W、放电时间240 s、氩气流量20 cm

/min、真空度22 Pa的条件下

在距放电中心0～30 cm范围内可实现对金黄色葡萄球菌的有效灭活(灭菌率≥99.9%); 在高放电功率下且氩气电离充分时

带电粒子(电子、离子)对菌体表面强烈的刻蚀作用是氩等离子体灭活金黄色葡萄球菌的主要原因

自由基对细菌的杀灭力小于带电粒子

而低放电功率下的灭菌则是由氩等离子体场中紫外光的作用所致.

Abstract

The germicidal effect(GE)and kinetics of Staphylococcus aureus by remote argon plasma are investigated

and the inactivation mechanism combining with the distribution of reactive species in the whole plasma field is discussed. The results show that the germicidal effect strongly depends on the experimental conditions

and with exposure time increasing

the kill rate slowers with three different segments. The effective inactivation appears within the distance of 0-30 cm(GE is no less that 99.9%)with the process parameters as follows: RF power of 100 W

time of 240 s

gas flow of 20 cm

/min

and pressure of 22 Pa. When the ionization degree of argon gas is sufficient under high power

the effectiveness of the remote argon plasma sterilization is believed to be attributed to the intense etching action on cell materials

which is initiated by discharge particles(electrons and

Ar ions)

the bombardment by free radicals is subsidiary. UV radiation in the plasma is the primary reason of bacterial inactivation under lower power.

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references

KACZMAREK H, KOWALONEK J, SZALLA A, et al. Surface modification of thin polymeric films by air-plasma or UV-irradiation [J]. Surface Science, 2002,507/510:883-888.

BALAZS D J, TRIANDAFILLU K, WOOD P, et al. Inhibition of bacterial adhesion on PVC endotracheal tubes by RF-oxygen glow discharge, sodium hydroxide and silver nitrate treatments [J]. Biomaterials, 2004, 25(11):2139-2151.

MOISAN M, BARBEAU J, MOREAU S, et al. Low-temperature sterilization using gas plasmas: a review of the experiments and an analysis of the inactivation mechanisms [J]. International Journal of Pharmaceutics, 2001,226(1/2):1-21.

LAROUSSI M, LEIPOLD F. Evaluation of the roles of reactive species, heat, and UV radiation in the inactivation of bacterial cells by air plasmas at atmospheric pressure [J]. International Journal of Mass Spectrometry, 2004,233(1/3):81-86.

CHOI J H, HAN I, BAIK H K, et al. Analysis of sterilization effect by pulsed dielectric barrier discharge [J]. Journal of Electrostatics, 2006,64:17-22.

刘红霞,陈杰瑢.远程氧等离子体灭菌对基质材料医用PTFE表面性能的影响 [J].西安交通大学学报,2009,43(3):82-86.

LIU Hongxia, CHEN Jierong. Influence of remote oxygen plasma sterilization on surface property of substrate material [J]. Journal of Xi'an Jiaotong University, 2009,43(3):82-86.

LIU Hongxia, CHEN Jierong. Analysis of surface sterilization and properties of medical poly(tetrafluoroe-thylene)in remote argon plasma [J]. IEEE Transactions on Plasma Science, 2008,36(1):230-236.

CHEN Jierong, YAN Jinglian, ZHANG Yuanze. Surface modification of medical PVC by remote oxygen plasma [J]. Composite Interfaces, 2004,11(2):123-130.

李茹, 李柯, 陈杰瑢. 远程氩等离子体表面改性对聚氯乙烯润湿性的影响[J].西安交通大学学报, 2005,39(9):1030-1034.

LI Ru, LI Ke, CHEN Jierong. Effects of wettability of medical polyvinyl chloride by remote argon plasma [J]. Journal of Xi'an Jiaotong University, 2005,39(9):1030-1034.

WANG Chen, CHEN Jierong, LI Ru. Studies on surface modification of poly(tetrafluoroethylene)film by remote and direct Ar plasma [J]. Applied Surface Science, 2008,254(9):2882-2888.

张文福. 医学消毒学 [M]. 北京:军事医学科学出版社,2002.

孙俊. 消毒技术与应用[M].北京:化学工业出版社,2003.

OSTRIKOV K N, DENYSENKO I B, TSAKADZE E L. Diagnostics and two-dimensional simulation of low-frequency inductively coupled plasmas with neutral gas heating and electron heat fluxes [J]. Journal of Applied Physics, 2002,92(9):4935-4946.

LI Yong, WANG Qi, GUO Jinliang. ESR studies on the interaction of calixarenes and free radicals [J]. Materials Science and Engineering: C, 1999,10:25-28.

ANNEMIE B, RENAAT G, WIM G. Comparison between a radio-frequency and direct current glow discharge in argon by a hybrid Monte Carlo-fluid model for electrons, argon ions and fast argon atoms [J]. Sectrochim Acta: B, 1999,54(9):1335-1350.

DHAYAL M, FORDER D, PARRY K L, et al. Using an afterglow plasma to modify polystyrene surfaces in pulsed radio frequency(RF)argon discharges [J]. Surface and Coatinqs Technology, 2003,173/174:872-876.

KO T M, COOPER S L. Surface properties and platelet adhesion characteristics of acrylic acid and allylamine plasma treated polyethylene [J]. Journal of Applied Polymer Science, 1993,47(1):1601-1619.

刘红霞,陈杰瑢.氩等离子体后辉光区对聚四氟乙烯膜表面优化改性的研究 [J].高等学校化学学报,2009,30(6): 1199-1204.

LIU Hongxia, CHEN Jierong. Optimizing the surface modification of poly(tetrafluoroethylene)in a flowing afterglow Ar plasma [J]. Chemical Journal of Chinese Universities, 2009,30(6):1199-1204.

LEROUGE S, FOZZA A C, WERTHEIMER M R, et al. Sterilization by low-pressure plasma: the role of vacuum-ultraviolet radiation [J]. Plasmas and Polymers, 2000,5(1):31-46.

SOLOSHENKO I O, KHOMICH V A, ISIOLKO V V, et al. Experimental and theoretical investigation of cold sterilization of medical instruments by plasma DC glow discharge [C]∥Proceedings of the 14th International Symposium on Plasma Chemistry. Prague, Czech Republic: Institute of Plasma Physics, 1999:2551-2555.

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