Experimental Investigation on Stenotic Artery Model with PIV Method

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Experimental Investigation on Stenotic Artery Model with PIV Method

更新时间：2025-07-09

- Experimental Investigation on Stenotic Artery Model with PIV Method
- Vol. 44, Issue 6, Pages: 120-124(2010)
- 作者机构：
  
  西安交通大学能源与动力工程学院,西安,710049
- 作者简介：
- 基金信息：
- DOI：
  CLC： Q811.6
- Online First：10 June 2010，
  
  Published：2010
- 稿件说明：
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Experimental Investigation on Stenotic Artery Model with PIV Method[J]. 2010, 44(6): 120-124.
DOI：

Experimental Investigation on Stenotic Artery Model with PIV Method[J]. 2010, 44(6): 120-124. DOI：

摘要

为了对狭窄血管内的剪切应力等流动力学参数及流场形态进行可视化测量

利用三维粒子速度场仪在不同雷诺数下对50%狭窄的颈动脉血管内的流场及剪切应力等流动参数进行了测量.实验结果表明

血管狭窄下游出现了较大范围低剪切应力区域

该区域内剪切应力值低于多数研究认为的能够避免血管内皮细胞损伤的最低值0.4 Pa(4 dyn/cm

).此结果支持了低剪切应力在血栓形成中起着重要作用的观点

同时血管狭窄处出现了较小范围的高剪切应力梯度区域

狭窄下游的涡流则会不断卷吸部分血液反复通过此区域造成血液成分受损

加速斑块的形成.

Abstract

Three-dimensional particle image velocimetry(3D-PIV)is applied in the artery model with a mild stenosis to investigate the flow field under different Reynolds number. A large area of low shear stress is observed at the stenosis downstream where plaque and stenosis are prone to evoke. This result verifies the hypothesis that low shear stress(less than 0.4 Pa(4 dyn/cm

))is vital in the formation of plaque and thrombosis. A high shear stress area is also observed at the stenosis position

and high shear stress gradient area exists at the boundary of low shear stress area and high shear stress area. Vortex at the downstream may rollback some blood through the high shear stress gradient area repeatedly and bring about damage to the blood ingredients

subsequently speed up the development of plaque.

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references

MCGILL H C Jr, MCMAHAN C A, GIDDING S S. Preventing heart disease in the 21st century: implications of the pathobiological determinants of atherosclerosis in youth(PDAY)study [J]. Circulation, 2008, 117(9):1216-1227.

JACKSON M, WOOD N, ZHAO S, et al. Low wall shear stress predicts subsequent development of wall hypertrophy in lower limb bypass grafts [J]. Artery Research, 2009, 3(1):32-38.

CHATZIZISIS Y S, COSKUN A U, JONAS M, et al. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodelling: molecular,cellular and vascular behavior [J]. Journal of the American College of Cardiology, 2007, 49(25): 2379-2393.

HENRY F S, COLLINS M W, HUGHES P E, et al. Numerical investigation of steady flow in proximal and distal end-to-side anastomoses[J]. Journal of Biomechanical Engineering, 1996, 118(3):302-310.

HE Xiaoyi, KU D N. Pulsatile flow in the human left coronary artery bifurcation: average conditions[J]. Journal of Biomechanical Engineering, 1996, 118(1):74-82.

BEMAD S, BERNAD E, SUSAN-RESIGA R F. Vorticity phenomena in biomedical contexts[C]∥Proceedings of the Workshop on Vortex Dominated Flows: Achievements and Open Problems. Timisoara, Romania: Imprimeria Mirton Press, 2005:169-176.

CHENG J W. Recognition, pathophysiology, and management of acute myocardial infarction[J]. American Journal of Health-System Pharmacy, 2001, 58(18):1709-1718.

XU X Y, COLLINS M W, JONES C J. Flow studies in canine artery bifurcations using a numerical simulation method[J]. Journal of Biomech Engineering, 1992, 114(4):504-511.

FATEMI R S, RITTGERS S E. Derivation of shear rates from near-wall LDA measurements under steady and pulsatile flow conditions [J]. Journal of Biomechanical Engineering, 1994, 116(3): 361-368.

RYUHEI Y, HIROSHI U, SAYAKA H, et al. Velocity profile and wall shear stress of saccular aneurysms at the anterior communicating artery[J]. Heart Vessels, 2008, 23(1):60-66.

KROLL M H, HELLUMS J D, MCLNTIRE L V, et al. Platelet and shear stress [J]. Blood, 1996, 88(5):1525-1541.

SLAGER C J, WWNTZEL J J, GIJSEN F J H, et al. The role of shear stress in the generation of rupture-prone vulnerable plaques [J]. Nature Clinical Practice Cardiovascular Medicine, 2005, 2(8):401-407.

BRAUNWALD E, ZIPES D P, LIBBY P, et al. Heart disease: a textbook of cardiovascular medicine[M]. Philadelphia,USA: WB Saunders Company, 2001:995-1009.

SHIMONO T, MAKINOUCHI K, YADA I, et al. New method of evaluating sub-lethal damage to erythrocytes by blood pumps [J]. Artificial Organs, 1996, 20(6):568-571.

CARO C G, PEDLEY R J, SCHROTER R C, et al. The mechanics of the circulation [M]. New York,USA: Oxford University Press, 1978:281.

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